Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7550506 | 0.83 | TSHR (0.47) | MAPK1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7638566 | 0.82 | LMNA (0.42) | MAPK1TSHRALDH1A1TP53HSD17B10 | |
| SCHEMBL7552814 | 0.80 | LMNA (0.40) | MAPK1ALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL7554929 | 0.79 | TSHR (0.40) | MAPK1TSHRALDH1A1TP53HSD17B10 | |
| SCHEMBL7554537 | 0.75 | KMT2A (0.54) | MAPK1ALDH1A1LMNAKMT2AALOX15 | |
| SCHEMBL7553433 | 0.75 | ALDH1A1 (0.37) | MAPK1ALDH1A1HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL6831109 | 0.74 | TSHR (0.57) | TSHRALDH1A1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL7550720 | 0.73 | LMNA (0.47) | MAPK1TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL7552015 | 0.73 | HSD17B10 (0.36) | TSHRALDH1A1HSD17B10MMP9SMN1; SMN2 | |
| SCHEMBL5186948 | 0.71 | KMT2A (0.47) | MAPK1TSHRALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734380-B1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6114538-A | 2-POSITION OF BENZOY RING OF 4-BENZOYLISOXAZOLE DERIVATIVE IS SUBSTITUTED AND PARTICULARLY USED AGAINST MONOCOTYLEDONOUS WEEDS BY POST-EMEREGENECE APPLICATION | RHONE POULENC AGRICULTURE LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| US-5998653-A | CHEMICAL INTERMEDIATE FOR HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1999-12-07 | — | — | US | disclosed |
| US-5658858-A | POSTEMERGENCE HERBICIDES | RHONE-POULENC ARGRICULTURE LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| CN-1137271-A | 4-benzoylisoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |