Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | BLM | P54132 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | FABP4 | P15090 | 2/20 | 0.30 |
| ▸ | F7 | P08709 | 2/20 | 0.30 |
| ▸ | F3 | P13726 | 2/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554520 | 1.00 | FAAH (0.34) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL7557885 | 0.87 | TRPV1 (0.32) | FAAHTRPV1 | |
| SCHEMBL7557881 | 0.87 | TRPV1 (0.32) | FAAHTRPV1 | |
| SCHEMBL995505 | 0.87 | FAAH (0.36) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL25185537 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL25185505 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL18837549 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL25178027 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL21694627 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT | |
| SCHEMBL21694630 | 0.85 | TOP1 (0.38) | FAAHTRPV1TOP1TERTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |