Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 3/20 | 0.34 |
| ▸ | TERT | O14746 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 2/20 | 0.31 |
| ▸ | F3 | P13726 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985159 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5985260 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5985893 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5984929 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5985932 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5987552 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5987035 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5984552 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5985975 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 | |
| SCHEMBL5985755 | 0.97 | FAAH (0.38) | FAAHTRPV1TOP1TERTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167278-A1 | TIRE RUBBER COMPOSITION AND TIRE | TOYO TIRE CORPORATION (JP) | 2023-06-01 | — | — | US | disclosed |
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-06-06 | — | — | US | disclosed |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| EP-3150663-B1 | ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER | BRIDGESTONE CORP (JP) | 2018-07-18 | — | — | EP | disclosed |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2018-04-05 | — | — | US | disclosed |
| EP-2151233-B1 | TWO-COMPONENT OXIDATIVE HAIR DYE COMPOSITION | KAO CORP (JP) | 2017-08-09 | — | — | EP | disclosed |
| US-20170204248-A1 | ANTI-VIBRATION RUBBER COMPOSITION AND ANTI-VIBRATION RUBBER | BRIDGESTONE CORPORATION (JP) | 2017-07-20 | — | — | US | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6685953-B1 | WATER RETENTION CAPACITY; MOISTURIZER; ALKOXYALKYAMIDES OF ALKYLENEDICARBOXYLIC ACIDS | KAO CORPORATION (JP) | 2004-02-03 | — | — | US | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-1166766-A1 | EXTERNAL PREPARATION COMPOSITIONS | Kao Corporation (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |
| EP-0738754-B1 | Rubber compositions | BRIDGESTONE CORP (JP) | 1998-11-25 | — | — | EP | disclosed |
| US-5705549-A | ISOBUTYLENE-BROMOMETHYLSTYRENE-VINYLTOLUENE TERPOLYMER, HYDRAZIDE | BRIDGESTONE CORPORATION (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0738754-A1 | Rubber compositions | Bridgestone Corporation (JP) | 1996-10-23 | — | — | EP | disclosed |
| US-5534569-A | KNEADING RUBBERS WITH CARBON BLACK, HYDRAZINE, HYDRAZIDE OR HYDANTOIN COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 1996-07-09 | — | — | US | disclosed |
| EP-0478274-A1 | Rubber composition | Bridgestone Corporation (JP) | 1992-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | FAAH 760/4885TRPV1 242/4885TOP1 3197/4885 |
| US-20180318294-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | FAAH 760/4885TRPV1 242/4885TOP1 3197/4885 |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, SULT2A1, CYP4Z1 | FAAH 401/4885TRPV1 211/4885TOP1 3704/4885 |
| US-20200061056-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | FAAH 760/4885TRPV1 242/4885TOP1 3197/4885 |
| US-20180092907-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | FAAH 760/4885TRPV1 242/4885TOP1 3197/4885 |
| US-20190167672-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | FAAH 760/4885TRPV1 242/4885TOP1 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.