Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | LTA4H | P09960 | 7/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549907 | 0.84 | HRH3 (0.47) | HRH3LTA4HSIGMAR1 | |
| SCHEMBL7108018 | 0.77 | HRH3 (0.43) | HRH3LTA4H | |
| SCHEMBL13499189 | 0.77 | HRH3 (0.55) | HRH3MEN1KMT2A | |
| SCHEMBL3434009 | 0.75 | HRH3 (0.48) | HRH3LTA4HMEN1KMT2A | |
| SCHEMBL4237405 | 0.74 | LTA4H (0.72) | HRH3LTA4HACHEBCHEMEN1 | |
| SCHEMBL8385088 | 0.73 | LTA4H (0.44) | LTA4HMEN1KMT2A | |
| SCHEMBL13499191 | 0.73 | HRH3 (0.56) | HRH3MEN1KMT2A | |
| SCHEMBL13149648 | 0.72 | NPC1 (0.74) | HRH3LTA4HMEN1NPC1RAB9A | |
| SCHEMBL3574322 | 0.72 | HRH3 (0.86) | HRH3ACHERAD52 | |
| SCHEMBL14287716 | 0.71 | HRH3 (0.83) | HRH3ACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183259-A2 | AZEPINOINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001023390-A2 | AZEPINOINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |