Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 6/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554518 | 0.84 | HRH3 (0.53) | HRH3LTA4HSIGMAR1 | |
| SCHEMBL7108018 | 0.83 | HRH3 (0.43) | HRH3KCNH2LTA4HPSMB1PSMB5 | |
| SCHEMBL3434009 | 0.78 | HRH3 (0.48) | HRH3KCNH2LTA4HCYP2C9ESR1 | |
| SCHEMBL21427 | 0.73 | NQO1 (0.47) | LTA4H | |
| SCHEMBL8542490 | 0.72 | MEN1 (0.53) | KDM4ECYP2C9 | |
| SCHEMBL4599631 | 0.72 | MEN1 (0.53) | KDM4ECYP2C9 | |
| SCHEMBL3348073 | 0.70 | MEN1 (0.54) | CYP2C9 | |
| SCHEMBL8385088 | 0.69 | LTA4H (0.44) | LTA4HCYP2C9 | |
| SCHEMBL27540906 | 0.68 | CACNA1F (0.44) | HRH3KDM4EESR1ESR2 | |
| SCHEMBL13499189 | 0.67 | HRH3 (0.55) | HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1183259-A2 | AZEPINOINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-06 | — | — | EP | disclosed |
| WO-2001023390-A2 | AZEPINOINDOLE DERIVATIVES, THE PRODUCTION AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-05 | — | — | WO | disclosed |