Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831106 | 1.00 | PTGS1 (0.59) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL8959967 | 1.00 | PTGS1 (0.59) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL10831356 | 0.86 | PTGS1 (0.68) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL10831605 | 0.86 | PTGS1 (0.68) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL5494789 | 0.86 | PTGS1 (0.68) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL27854366 | 0.83 | PTGS1 (0.59) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL7040469 | 0.82 | PTGS1 (0.77) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL7032448 | 0.82 | PTGS1 (0.77) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL5527572 | 0.81 | L3MBTL1 (0.65) | F10ALDH1A1L3MBTL1 | |
| SCHEMBL10831167 | 0.81 | PTGS1 (0.60) | PTGS1ALOX5MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4607119-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-19 | — | — | US | claimed |
| EP-0946495-B1 | PHENYL ACETAMIDES AS SPLA2 INHIBITORS | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0569461-B1 | NOVEL PYRETHROID COMPOSITION | FMC CORP (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0569461-A1 | NOVEL PYRETHROID COMPOSITION. | FMC CORP (US) | 1993-11-18 | — | — | EP | disclosed |
| EP-0569461-A4 | NOVEL PYRETHROID COMPOSITION. | FMC CORP (US) | 1993-09-07 | — | — | EP | disclosed |
| US-5164411-A | Mixture of cypermethrin isomers | FMC CORPORATION (US) | 1992-11-17 | — | — | US | disclosed |
| WO-1992012634-A1 | NOVEL PYRETHROID COMPOSITION | FMC CORPORATION (US) | 1992-08-06 | — | — | WO | disclosed |
| US-4970330-A | INSECTICIDES, PESTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-13 | — | — | US | disclosed |
| US-4607119-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-19 | — | — | US | disclosed |
| US-4391983-A | Carboxamidoesters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-07-05 | — | — | US | disclosed |
| US-4378316-A | INTERMEDIATES FOR CYCLOPROPANE-CARBOXYLIC ESTERS; INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-03-29 | — | — | US | disclosed |
| US-4330675-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-05-18 | — | — | US | disclosed |
| US-4183948-A | INSECTICIDE SYNERGIST | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4146554-A | BY DEHYDRATION OF CORRESPONDING AMIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |