Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10831605 | 1.00 | PTGS1 (0.68) | PTGS1LMNAMAPK1MEN1CYP2D6 | |
| SCHEMBL10831356 | 1.00 | PTGS1 (0.68) | PTGS1LMNAMAPK1MEN1CYP2D6 | |
| SCHEMBL10831106 | 0.86 | PTGS1 (0.59) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL7554763 | 0.86 | PTGS1 (0.59) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8959967 | 0.86 | PTGS1 (0.59) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8796964 | 0.84 | PTGS1 (0.70) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10831170 | 0.83 | PTGS1 (0.60) | PTGS1MAPK1MEN1CYP2D6KMT2A | |
| SCHEMBL10831167 | 0.83 | PTGS1 (0.60) | PTGS1MAPK1MEN1CYP2D6KMT2A | |
| SCHEMBL23053345 | 0.83 | LMNA (0.65) | PTGS1LMNAMAPK1SRD5A2NPY5R | |
| SCHEMBL7453363 | 0.83 | LMNA (0.65) | PTGS1LMNAMAPK1SRD5A2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102807614-A | Hapten synthesis method of pyrethroids alpha-carboxy ethyl sulfur formyl deltamethrin | HUAIYIN INST TECHNOLOGY | 2012-12-05 | — | — | CN | claimed |
| CN-100340543-C | Cyfluthrin hapten compound, its synthesis method and use | UNIV ZHEJIANG (CN) | 2007-10-03 | — | — | CN | claimed |
| US-4607119-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-08-19 | — | — | US | claimed |
| JP-54016442-A | — | — | None | — | — | JP | disclosed |
| JP-54130536-A | — | — | None | — | — | JP | disclosed |
| JP-53098938-A | — | — | None | — | — | JP | disclosed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2023-10-26 | — | — | US | disclosed |
| WO-2021221169-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | RAQUALIA PHARMA INC. (JP) | 2021-11-04 | — | — | WO | disclosed |
| US-20150094474-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROTECTION LTD (GB) | 2015-04-02 | — | — | US | disclosed |
| EP-2825527-A1 | AGRICULTURAL CHEMICALS | Redx Pharma Limited (GB) | 2015-01-21 | — | — | EP | disclosed |
| US-4303585-A | 3-Oxa-bicyclo (3,1,0)-hexan-2-one intermediates | ROUSSEL UCLAF (FR) | 1981-12-01 | — | — | US | disclosed |
| US-4273727-A | INSECTICIDE INTERMEDIATES | ROUSSEL UCLAF (FR) | 1981-06-16 | — | — | US | disclosed |
| EP-0005779-B1 | PROCESS FOR THE PREPARATION OF ARYLGLYOXYLIC ACIDS | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |
| EP-0005779-A2 | Process for the preparation of arylglyoxylic acids | BAYER AG (DE) | 1979-12-12 | — | — | EP | disclosed |
| JP-S54130536-A | OPTICAL ACTIVE CYANOO33PHENOXYBENZYLL2*2*3*33TETRAMETHYLL CYCLOPROPANE CARBOXYLATE AND INSECTICIDE MITICIDE CONTAINING THE SAME AS EFFECTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1979-10-09 | — | — | JP | disclosed |
| US-4146554-A | BY DEHYDRATION OF CORRESPONDING AMIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
| JP-S5416442-A | OPTICAL RESOLUTION OF 3-PHEOXYMANDELIC ACID | SUMITOMO CHEM CO LTD | 1979-02-07 | — | — | JP | disclosed |
| JP-S5398938-A | NOVEL PROCESS FOR THEIR PREPARATION OF INSECTICIDES | SUMITOMO CHEM CO LTD | 1978-08-29 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094474-A1 | AGRICULTURAL CHEMICALS | DDT, SQOR, GPX4 | PTGS1 890/4885LMNA 4681/4885MAPK1 2198/4885 |
| US-20230339934-A1 | PYRIMIDIN-4(3H)-ONE DERIVATIVES AS TRPV4 ANTAGONISTS | TRPV4, TRPV1, TRPV2 | PTGS1 135/4885LMNA 4199/4885MAPK1 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.