SCHEMBL7555107

SCHEMBL7555107

Fc1ccc2cc3c(cc2c1)-c1cccc2cccc-3c12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
HSD17B10 Q99714 5/20 0.65
TSHR P16473 4/20 0.65
MAPK1 P28482 4/20 0.65
HPGD P15428 4/20 0.65
CASP1 P29466 3/20 0.65
CASP7 P55210 2/20 0.65
HIF1A Q16665 2/20 0.65
TP53 P04637 1/20 0.65
CYP1A2 P05177 2/20 0.56
CYP2A6 P11509 1/20 0.56
L3MBTL1 Q9Y468 4/20 0.48
ATM Q13315 3/20 0.48
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
CES2 O00748 1/20 0.40
BCHE P06276 1/20 0.40
CES1 P23141 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16200908 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10TSHRMAPK1HPGD
SCHEMBL4853854 0.81 ALDH1A1 (0.90) ALDH1A1HSD17B10TSHRMAPK1HPGD
Benzo(K)Fluoranthene SCHEMBL29393074 0.80 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1HPGD
Benzo(K)Fluoranthene SCHEMBL175484 0.80 ALDH1A1 (1.00) ALDH1A1HSD17B10TSHRMAPK1HPGD
SCHEMBL2580472 0.75 CYP2A6 (0.84) ALDH1A1HSD17B10HPGDCASP1CASP7
SCHEMBL1310942 0.75 CYP2A6 (0.84) ALDH1A1HSD17B10HPGDCASP1CASP7
SCHEMBL8789837 0.75 CYP2A6 (0.84) ALDH1A1HSD17B10HPGDCASP1CASP7
SCHEMBL3717126 0.73 CYP1A2 (0.64) ALDH1A1TSHRMAPK1CASP1CASP7
SCHEMBL935337 0.73 CYP2A6 (1.00) ALDH1A1HSD17B10CYP1A2CYP2A6L3MBTL1
SCHEMBL18087081 0.73 CYP2A6 (1.00) ALDH1A1HSD17B10CYP1A2CYP2A6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1221044-A2 MONOFLUORINATED POLYCYCLIC AROMATIC COMPOUNDS AND THE USE THEREOF AS ADDITIVE POLYCYCLIC AROMATIC COMPOUNDS IN PHYSICAL, CHEMICAL AND BIOLOGICAL PROCESSES Luthe, Gregor (DE) 2002-07-10 EP disclosed
WO-2001029555-A2 MONOFLUORINATED POLYCYCLIC AROMATIC COMPOUNDS AND THE USE THEREOF AS ADDITIVE POLYCYCLIC AROMATIC COMPOUNDS LUTHE GREGOR (DE) 2001-04-26 WO disclosed