SCHEMBL755512

SCHEMBL755512

C=C(C)COCC(C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)OC(O)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20953856 0.78 TSHR (0.31) TSHR
SCHEMBL3627739 0.77
SCHEMBL755618 0.75 TSHR (0.30) TSHR
SCHEMBL9301559 0.74
SCHEMBL9303046 0.74
SCHEMBL17743494 0.72 TSHR (0.35) TSHR
SCHEMBL396760 0.69
SCHEMBL1943348 0.68
SCHEMBL396531 0.68
SCHEMBL2189977 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207825-B8 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2012-03-21 EP claimed
EP-2207825-B1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2011-06-29 EP claimed
JP-2011502198-A 2011-01-20 JP claimed
EP-2207825-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS Johnson & Johnson Vision Care, Inc. (US) 2010-07-21 EP claimed
EP-1809344-B1 BIOMEDICAL DEVICES CONTAINING AMPHIPHILIC BLOCK COPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2010-01-20 EP claimed
WO-2009058207-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2009-05-07 WO claimed
US-20090111905-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. 2009-04-30 US claimed
EP-2207825-B8 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2012-03-21 EP disclosed
EP-2207825-B1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE (US) 2011-06-29 EP disclosed
EP-2207825-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS Johnson & Johnson Vision Care, Inc. (US) 2010-07-21 EP disclosed
WO-2009058207-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. (US) 2009-05-07 WO disclosed
US-20090111905-A1 PROCESS FOR FORMING RANDOM (METH)ACRYLATE CONTAINING PREPOLYMERS JOHNSON & JOHNSON VISION CARE, INC. 2009-04-30 US disclosed