Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 4/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAP2 | P11137 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1381646 | 0.82 | HK2 (0.40) | BRD4GRIA4GRIA2FABP3FABP4 | |
| SCHEMBL7005559 | 0.79 | KMT2A (0.42) | BRD4GRIA4GRIA2KMT2AMEN1 | |
| SCHEMBL7005204 | 0.77 | TPMT (0.36) | AKR1C2ACLYKDM4EALDH1A1GAA | |
| SCHEMBL1381890 | 0.73 | FGFR1 (0.42) | KMT2A | |
| SCHEMBL1081579 | 0.70 | GRIA4 (0.47) | BRD4GRIA4GRIA2KMT2AMEN1 | |
| SCHEMBL3631608 | 0.68 | MEN1 (0.42) | KMT2AMEN1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7004832 | 0.67 | BAZ2B (0.50) | KDM4EALDH1A1GAA | |
| SCHEMBL8287396 | 0.66 | GRIA4 (0.59) | GRIA4GRIA2 | |
| SCHEMBL5231452 | 0.66 | DPP4 (0.46) | GRIA4GRIA2 | |
| SCHEMBL7008527 | 0.65 | BAZ2B (0.45) | KMT2AMEN1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |