Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557956 | 0.91 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3DRD2HTT | |
| SCHEMBL7557202 | 0.85 | LMNA (0.33) | — | |
| SCHEMBL7553419 | 0.84 | SLC6A4 (0.36) | SLC6A2SLC6A4SLC6A3DRD2MEN1 | |
| SCHEMBL7554533 | 0.83 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL7550331 | 0.82 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3CHRM2CHRM1 | |
| SCHEMBL7552036 | 0.81 | ALDH1A1 (0.34) | SLC6A2SLC6A4MEN1CYP1A2CYP3A4 | |
| SCHEMBL7552294 | 0.81 | SLC6A4 (0.35) | SLC6A2SLC6A4SLC6A3DRD2MEN1 | |
| SCHEMBL7554657 | 0.81 | CLCN2 (0.35) | HTTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7553022 | 0.81 | SLC6A2 (0.33) | SLC6A2SLC6A4SLC6A3CYP3A4KMT2A | |
| SCHEMBL8145066 | 0.80 | KMT2A (0.37) | DRD2DRD3HTTMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734380-B1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6369270-B1 | CHEMICAL INTERMEDIATES | RHONE POULENC AGRICULTURE LIMITED (GB) | 2002-04-09 | — | — | US | disclosed |
| US-5998653-A | CHEMICAL INTERMEDIATE FOR HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1999-12-07 | — | — | US | disclosed |
| US-5658858-A | POSTEMERGENCE HERBICIDES | RHONE-POULENC ARGRICULTURE LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |