Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.73 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5238032 | 0.99 | DPP4 (0.71) | DPP4KCNA5KCNH2PRKCAGSK3B | |
| SCHEMBL5236192 | 0.90 | DPP4 (0.58) | DPP4KCNA5KCNH2PRKCAGSK3B | |
| SCHEMBL5238950 | 0.89 | DPP4 (0.57) | DPP4KCNA5KCNH2PRKCAGSK3B | |
| SCHEMBL7006788 | 0.87 | DPP4 (0.74) | DPP4KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL5240250 | 0.86 | DPP4 (0.72) | DPP4KCNA5KCNH2 | |
| SCHEMBL5232770 | 0.85 | DPP4 (1.00) | DPP4KCNA5KCNH2 | |
| Hydrochloric Acid SCHEMBL5235851 | 0.84 | DPP4 (0.76) | DPP4KCNA5KCNH2BRD4 | |
| SCHEMBL7007690 | 0.84 | DPP4 (0.76) | DPP4KCNA5KCNH2 | |
| SCHEMBL5235258 | 0.83 | DPP4 (0.53) | DPP4KCNA5KCNH2PRKCAGSK3B | |
| SCHEMBL5232687 | 0.83 | DPP4 (0.53) | DPP4KCNA5KCNH2PRKCAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |