Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7555706

N.Nc1ccc(Oc2ccc(N)cc2S(=O)(=O)O)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.47
POLB P06746 4/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
L3MBTL1 Q9Y468 3/20 0.45
APEX1 P27695 2/20 0.45
RXFP1 Q9HBX9 2/20 0.45
ALDH1A1 P00352 9/20 0.42
MAPT P10636 5/20 0.42
TDP1 Q9NUW8 4/20 0.42
GAA P10253 3/20 0.42
TSHR P16473 3/20 0.42
KDM4E B2RXH2 2/20 0.42
RECQL P46063 2/20 0.42
CASP6 P55212 2/20 0.42
CYP3A4 P08684 1/20 0.42
NSD2 O96028 1/20 0.42
APOBEC3A P31941 1/20 0.42
APOBEC3G Q9HC16 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2120389 0.98 RAPGEF4 (0.49) RAPGEF4POLBMEN1KMT2AL3MBTL1
Trimethylammonium SCHEMBL7550916 0.92 POLB (0.45) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL1259167 0.92 POLB (0.44) RAPGEF4POLBMEN1KMT2AL3MBTL1
Ammonia Solution, Strong SCHEMBL7550375 0.90 RAPGEF4 (0.49) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL11659131 0.89 KMT2A (0.49) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL1030592 0.89 POLB (0.44) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL8769337 0.89 POLB (0.56) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL31184477 0.88 RAPGEF4 (0.50) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL487024 0.88 RAPGEF4 (0.50) RAPGEF4POLBMEN1KMT2AL3MBTL1
SCHEMBL7551579 0.87 HSD17B10 (0.43) RAPGEF4POLBMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0747418-B1 Aromatic polyimide and gas separation UBE INDUSTRIES (JP) 2002-07-03 EP disclosed
US-5744575-A Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1998-04-28 US disclosed
EP-0747418-A1 Aromatic polyimide and gas separation UBE INDUSTRIES, LTD. (JP) 1996-12-11 EP disclosed