Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 20/20 | 0.55 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.55 |
| ▸ | PGR | P06401 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | MLNR | O43193 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059354 | 1.00 | CYP3A4 (0.55) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL5365349 | 0.91 | CYP3A4 (0.57) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL4959493 | 0.87 | CYP3A4 (0.62) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL893239 | 0.87 | CYP3A4 (0.62) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL4959500 | 0.87 | CYP3A4 (0.62) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL9944056 | 0.81 | CYP3A4 (0.61) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL893086 | 0.81 | CYP3A4 (0.61) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL893553 | 0.81 | CYP3A4 (0.61) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL893460 | 0.81 | CYP3A4 (0.62) | CYP3A4ABCC3ABCC4ABCB11PGR | |
| SCHEMBL2954848 | 0.81 | CYP3A4 (0.62) | CYP3A4ABCC3ABCC4ABCB11PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472529-B2 | VIRICIDES | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| US-20020004503-A1 | Retroviral protease inhibiting compounds | ABBVIE INC. | 2002-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020004503-A1 | Retroviral protease inhibiting compounds | SERPINB1, PREP, TMPRSS15 | CYP3A4 1600/4885ABCC3 2311/4885ABCC4 2547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.