Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17135973 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL2735553 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL11237755 | 0.98 | ALDH1A1 (0.49) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL11237751 | 0.98 | ALDH1A1 (0.49) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL11342557 | 0.79 | ALDH1A1 (0.37) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL7537547 | 0.76 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL7542696 | 0.76 | ALDH1A1 (0.48) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL11206930 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL11206934 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPSR1KDM4EHTTTDP1 | |
| SCHEMBL1931577 | 0.75 | ALDH1A1 (0.43) | ALDH1A1NPSR1KDM4EHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4347683-B1 | CURABLE PHOTOCHROMIC COMPOSITION | TRANSITIONS OPTICAL LTD (IE) | 2026-05-06 | — | — | EP | disclosed |
| EP-4727984-A1 | CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING (METH)ACRYLATE, AMINE, AND ISOCYANATE FUNCTIONAL COMPONENTS | Transitions Optical, Ltd. (IE) | 2026-04-22 | — | — | EP | disclosed |
| US-12570787-B2 | Curable compositions and articles prepared therefrom | TRANSITIONS OPTICAL, LTD. (IE) | 2026-03-10 | — | — | US | disclosed |
| US-20250361353-A1 | Curable Photochromic Compositions Including Isocyanate and Imine Functional Components | TRANSITIONS OPTICAL LTD (IE) | 2025-11-27 | — | — | US | disclosed |
| US-12304991-B2 | Photochromic article | TRANSITIONS OPTICAL, LTD. (IE) | 2025-05-20 | — | — | US | disclosed |
| US-12240996-B2 | Curable photochromic composition including a segmented polymer | TRANSITIONS OPTICAL, LTD. (IE) | 2025-03-04 | — | — | US | disclosed |
| EP-3877433-B1 | PHOTOCHROMIC ARTICLE | TRANSITIONS OPTICAL LTD (IE) | 2025-01-08 | — | — | EP | disclosed |
| WO-2024255988-A1 | CURABLE PHOTOCHROMIC COMPOSITIONS INCLUDING (METH)ACRYLATE, AMINE, AND ISOCYANATE FUNCTIONAL COMPONENTS | TRANSITIONS OPTICAL, LTD. (IE) | 2024-12-19 | — | — | WO | disclosed |
| US-20240254275-A1 | Curable Photochromic Composition | TRANSITIONS OPTICAL, LTD. (IE) | 2024-08-01 | — | — | US | disclosed |
| EP-4347683-A1 | CURABLE PHOTOCHROMIC COMPOSITION | Transitions Optical, Ltd. (IE) | 2024-04-10 | — | — | EP | disclosed |
| WO-2019029794-A1 | CURABLE PHOTOCHROMIC COMPOSITION INCLUDING A SEGMENTED POLYMER | TRANSITIONS OPTICAL, LTD. (IE) | 2019-02-14 | — | — | WO | disclosed |
| US-9040648-B2 | Polymer compositions containing mechanochromic polymers | PPG INDUSTRIES OHIO, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| US-8889807-B2 | Controlled radical polymerization initiators | PPG INDUSTRIES OHIO, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| WO-2014152259-A1 | POLYMER COMPOSITIONS CONTAINING MECHANOCHROMIC POLYMERS | PPG INDUSTRIES OHIO, INC. (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20130273380-A1 | CONTROLLED RADICAL POLYMERIZATION INITIATORS | PPG INDUSTRIES OHIO, INC.. | 2013-10-17 | — | — | US | disclosed |
| US-20130274412-A1 | POLYMER COMPOSITIONS CONTAINING MECHANOCHROMIC POLYMERS | PPG INDUSTRIES OHIO, INC. | 2013-10-17 | — | — | US | disclosed |
| US-6482475-B2 | POWDER COATING | PPG INDUSTRIES OHIO, INC. | 2002-11-19 | — | — | US | disclosed |
| US-20020012751-A1 | Thermosetting compositions containing hydroxy functional polymers prepared by atom transfer radical polymerization | BARKAC KAREN A (US) | 2002-01-31 | — | — | US | disclosed |
| US-6319988-B1 | LIVING BLOCK POLYMER FROM HYDROXY-FUNCTIONAL UNSATURATED MONOMERS AND OTHER MONOMERS ENDCAPPED WITH SULFONYL HALIDE OR A DIETHYL MALONATE (PREFERABLY A-HALO-SUBSTITUTED); BLOCKED POLYISOCYANATE CROSSLINKING AGENT; LOWER VISCOSITIES | PPG INDUSTRIES OHIO, INC. | 2001-11-20 | — | — | US | disclosed |
| WO-2000012579-A1 | THERMOSETTING COMPOSITIONS CONTAINING HYDROXY FUNCTIONAL POLYMERS PREPARED BY ATOM TRANSFER RADICAL POLYMERIZATION | PPG INDUSTRIES OHIO, INC. (US) | 2000-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570787-B2 | Curable compositions and articles prepared therefrom | EHMT2, EHMT1, BHMT2 | ALDH1A1 1039/4885NPSR1 4801/4885KDM4E 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.