Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592119 | 0.85 | ALDH1A1 (0.35) | TSHRALDH1A1SMN1; SMN2VCAM1MAPT | |
| SCHEMBL17667803 | 0.81 | TSHR (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2VCAM1 | |
| SCHEMBL6834233 | 0.81 | MAPK1 (0.47) | TSHRMAPK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2958270 | 0.81 | APP (0.39) | TSHRALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL21239 | 0.80 | ALDH1A1 (0.47) | TSHRALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL6834096 | 0.80 | ALDH1A1 (0.44) | TSHRMAPK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4308070 | 0.79 | ALDH1A1 (0.46) | TSHRMAPK1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4300511 | 0.79 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2VCAM1 | |
| SCHEMBL7781943 | 0.79 | MAPK1 (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2VCAM1 | |
| SCHEMBL2955824 | 0.77 | MAPK1 (0.50) | MAPK1ALDH1A1VCAM1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224198-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001032671-A1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTING GROUPS | NIGU CHEMIE GMBH (DE) | 2001-05-10 | — | — | WO | disclosed |