Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299909 | 0.83 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL2958270 | 0.83 | APP (0.39) | ALDH1A1CYP1A2TSHRTDP1LMNA | |
| SCHEMBL7873069 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL994480 | 0.81 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL299908 | 0.81 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL7592119 | 0.81 | ALDH1A1 (0.35) | ALDH1A1CYP1A2TSHRSMN1; SMN2NPC1 | |
| SCHEMBL7555813 | 0.80 | TSHR (0.44) | ALDH1A1TSHRSMN1; SMN2TDP1LMNA | |
| SCHEMBL12932112 | 0.80 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL21240 | 0.79 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 | |
| SCHEMBL291947 | 0.79 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 414 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110477-A2 | SYNTHESIS OF A CYCLIC PEPTIDE | JANSSEN PHARMACEUTICA NV (BE) | 2024-05-30 | — | — | WO | claimed |
| US-20240042101-A1 | PHOTOPATTERNED BIOMOLECULE IMMOBILIZATION TO GUIDE 3D CELL FATE IN NATURAL PROTEIN-BASED HYDROGELS | UNIVERSITY OF WASHINGTON (US) | 2024-02-08 | — | — | US | claimed |
| US-20230092024-A1 | Increasing Efficiency Of Photochemical Reactions On Substrates | CENTRILLION TECHNOLOGIES, INC. | 2023-03-23 | — | — | US | claimed |
| EP-4140988-A1 | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | Merck Serono S.A. (CH) | 2023-03-01 | — | — | EP | claimed |
| EP-4107782-A1 | MICROARRAYS | Polymer Forge, Inc. (US) | 2022-12-28 | — | — | EP | claimed |
| WO-2022140269-A1 | PHOTOPATTERNED BIOMOLECULE IMMOBILIZATION TO GUIDE 3D CELL FATE IN NATURAL PROTEIN-BASED HYDROGELS | UNIVERSITY OF WASHINGTON (US) | 2022-06-30 | — | — | WO | claimed |
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2019-05-14 | — | — | US | claimed |
| EP-2748176-B1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) | 2019-04-17 | — | — | EP | claimed |
| EP-3400217-A1 | L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF | Merck Serono S.A. (CH) | 2018-11-14 | — | — | EP | claimed |
| US-20180149611-A1 | BIOSENSOR AND METHOD OF FORMING PROBE ON SOLID SURFACE OF BIOSENSOR | Caduceus Biotechnology Inc. (TW) | 2018-05-31 | — | — | US | claimed |
| US-20070060744-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2007-03-15 | — | — | US | claimed |
| US-20060014943-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2006-01-19 | — | — | US | claimed |
| US-6962991-B2 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2005-11-08 | — | — | US | claimed |
| US-20040197851-A1 | Two-stage protective groups for the synthesis of biopolymers | MR. CHRISTOPHER SEAGON, ESQ. (DE) | 2004-10-07 | — | — | US | claimed |
| US-20040191824-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. | 2004-09-30 | — | — | US | claimed |
| EP-1427743-A2 | PROCESS FOR THE SYNTHESIS OF PYRAZOLOPYRIMIDINES | Epoch Biosciences, Inc. (US) | 2004-06-16 | — | — | EP | claimed |
| EP-1401851-A1 | TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS | Febit AG (DE) | 2004-03-31 | — | — | EP | claimed |
| US-20030078413-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. | 2003-04-24 | — | — | US | claimed |
| WO-2003022859-A2 | PROCESS FOR THE SYNTHESIS OF PYRAZOLOPYRIMIDINES | EPOCH BIOSCIENCES, INC. (US) | 2003-03-20 | — | — | WO | claimed |
| WO-2003004510-A1 | TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS | FEBIT AG (DE) | 2003-01-16 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287313-B2 | RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays | EFTUD2, RNMT, NSUN2 | ALDH1A1 199/4885CYP1A2 3340/4885TSHR 4669/4885 |
| US-20040197851-A1 | Two-stage protective groups for the synthesis of biopolymers | CTRB2, OGG1, CPB2 | ALDH1A1 1433/4885CYP1A2 474/4885TSHR 4581/4885 |
| US-20030078413-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20060014943-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20070060744-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20230092024-A1 | Increasing Efficiency Of Photochemical Reactions On Substrates | TYR, PCNA, DNMT1 | ALDH1A1 1455/4885CYP1A2 615/4885TSHR 4716/4885 |
| US-20240042101-A1 | PHOTOPATTERNED BIOMOLECULE IMMOBILIZATION TO GUIDE 3D CELL FATE IN NATURAL PROTEIN-BASED HYDROGELS | BTD, HLCS, PTMS | ALDH1A1 403/4885CYP1A2 2434/4885TSHR 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.