Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 7/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7903400 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL7555821 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL7555825 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL7892475 | 0.87 | CYP3A4 (0.33) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL7892621 | 0.86 | GRM5 (0.36) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL7892659 | 0.84 | HSD17B2 (0.41) | ALDH1A1CYP3A4MAPTHPGDCYP2C9 | |
| SCHEMBL31037751 | 0.72 | L3MBTL1 (0.37) | ALDH1A1HPGDCYP2C9HSD17B2LMNA | |
| SCHEMBL2170851 | 0.70 | HSD17B2 (0.40) | ALDH1A1CYP3A4CYP2C19HSD17B2L3MBTL1 | |
| SCHEMBL2170846 | 0.70 | HSD17B2 (0.40) | ALDH1A1CYP3A4CYP2C19HSD17B2L3MBTL1 | |
| SCHEMBL23849944 | 0.66 | CYP3A4 (0.38) | ALDH1A1CYP3A4HPGDCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |