Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | THRA | P10827 | 3/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19944270 | 0.84 | THRB (0.45) | THRBTHRAS1PR1S1PR4S1PR5 | |
| SCHEMBL5211499 | 0.83 | POLB (0.40) | LMNA | |
| SCHEMBL1446424 | 0.83 | THRB (0.64) | THRBTHRAS1PR1S1PR4S1PR5 | |
| SCHEMBL3410792 | 0.82 | THRB (0.53) | THRBTHRAMEN1ALDH1A1LMNA | |
| SCHEMBL9624655 | 0.82 | S1PR1 (0.49) | THRBTHRAS1PR1S1PR4S1PR5 | |
| Methacrylic Acid SCHEMBL6434237 | 0.81 | S1PR1 (0.54) | THRBTHRAS1PR1S1PR4S1PR5 | |
| SCHEMBL9624089 | 0.81 | S1PR1 (0.50) | THRBTHRAS1PR1S1PR4S1PR5 | |
| SCHEMBL13397686 | 0.81 | THRB (0.51) | THRBTHRAS1PR1S1PR4S1PR5 | |
| SCHEMBL14173290 | 0.80 | ACACB (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL14173282 | 0.80 | ACACB (0.47) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783023-B1 | Polymeric dispersants for pigmented inks | LEXMARK INT INC (US) | 2002-03-13 | — | — | EP | claimed |
| US-20160208127-A1 | COMPOSITION AND FILM | TOYO GOSEI CO., LTD. (JP) | 2016-07-21 | — | — | US | disclosed |