SCHEMBL7556433

SCHEMBL7556433

CCC/C=C/COC(=O)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
PTGS1 P23219 1/20 0.33
FAAH O00519 3/20 0.33
TSHR P16473 1/20 0.32
HDAC3 O15379 2/20 0.32
HDAC1 Q13547 2/20 0.32
HDAC6 Q9UBN7 2/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
DGKA P23743 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7556437 1.00 TAS1R3 (0.35) TAS1R3TAS1R1PTGS1FAAHTSHR
SCHEMBL30902191 0.87 TSHR (0.34) TSHR
SCHEMBL11652697 0.87 TSHR (0.34) TSHR
SCHEMBL11652702 0.87 TSHR (0.34) TSHR
SCHEMBL5934594 0.86 TAS1R3 (0.34) TAS1R3TAS1R1PTGS1FAAHTSHR
SCHEMBL5934595 0.86 TAS1R3 (0.34) TAS1R3TAS1R1PTGS1FAAHTSHR
SCHEMBL11808432 0.85 FAAH (0.50) PTGS1FAAHDGKA
SCHEMBL11808420 0.85 FAAH (0.50) PTGS1FAAHDGKA
SCHEMBL18055666 0.84 FAAH (0.33) TAS1R3TAS1R1PTGS1FAAHCNR1
SCHEMBL3505963 0.84 FAAH (0.33) TAS1R3TAS1R1PTGS1FAAHCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3974196-A Method for disproportionating ethylenically unsaturated compounds having functional ester groups JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1976-08-10 US claimed
EP-0626402-B1 Linear telechelic difunctional polymers and process for their preparation. CALIFORNIA INST OF TECHN (US) 2002-07-31 EP disclosed
US-5731383-A USED FOR HIGH DENSITY POLYESTERS, POLYAMIDES, POLYUREAS, POLYURETHANES AMOCO CORPORATION (US) 1998-03-24 US disclosed
US-5589548-A Process for preparing difunctional telechelic linear non-crosslinked polyolefins AMOCO CORPORATION (US) 1996-12-31 US disclosed
US-5559190-A Difunctional telechelic linear non-crosslinked polyolefins AMOCO CORPORATION (US) 1996-09-24 US disclosed
US-5512635-A OLEFIN METATHESIS PROCESS; CROSSLINKING INHIBITION AMOCO CORPORATION (US) 1996-04-30 US disclosed
US-5403904-A Process for preparation of telechelic difunctional unsaturated oligomers or polymers by acyclic olefin metathesis AMOCO CORPORATION (US) 1995-04-04 US disclosed
EP-0626402-A2 Process for preparing linear monofunctional and telechelic difunctional polymers and compositions obtained thereby AMOCO CORPORATION (US) 1994-11-30 EP disclosed
US-4217299-A Method for converting unsaturated compound having functional group JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1980-08-12 US disclosed
US-4117110-A GELS, DEODORIZERS GLOBOL WERK GMBH (DE) 1978-09-26 US disclosed
US-3974196-A Method for disproportionating ethylenically unsaturated compounds having functional ester groups JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1976-08-10 US disclosed