Phenylacetic Acid

Phenylacetic Acid

SCHEMBL7556535

Cc1ccc(N)cc1.O=C(O)Cc1ccccc1

nearest known ligand 0.63

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.63
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.50
ABCC4 O15439 1/20 0.50
GAA P10253 1/20 0.50
TSHR P16473 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
CNR2 P34972 2/20 0.49
CNR1 P21554 1/20 0.49
ACHE P22303 1/20 0.48
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
KDM4E B2RXH2 1/20 0.47
F2 P00734 1/20 0.47
POLB P06746 1/20 0.47
PAM P19021 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylacetic Acid SCHEMBL28136535 0.90 AKR1B1 (0.77) AKR1B1L3MBTL1TDP1LMNAABCC4
SCHEMBL22068412 0.86 AKR1B1 (0.77) AKR1B1LMNAABCC4GAATSHR
Phenylacetic Acid SCHEMBL10870034 0.86 AKR1B1 (0.77) AKR1B1L3MBTL1TDP1LMNAABCC4
Phenylacetic Acid SCHEMBL8319811 0.83 CA2 (0.67) AKR1B1L3MBTL1TDP1LMNAABCC4
SCHEMBL39103 0.82 CA2 (0.62) AKR1B1TDP1LMNAABCC4GAA
SCHEMBL2525145 0.82 CA2 (0.62) AKR1B1L3MBTL1TDP1LMNAABCC4
Phenylacetic Acid SCHEMBL28199060 0.82 AKR1B1 (0.85) AKR1B1LMNAABCC4GAATSHR
SCHEMBL92022 0.82 CA2 (0.62) AKR1B1L3MBTL1TDP1LMNAABCC4
SCHEMBL1331730 0.82 CA2 (0.62) AKR1B1TDP1LMNAABCC4GAA
4-Methylbenzoic Acid SCHEMBL8360450 0.81 ALDH1A1 (0.63) AKR1B1L3MBTL1TDP1LMNAABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002059655-A THERMAL RECORDING MATERIAL SAITO KASEIHIN KENKYUSHO:KK 2002-02-26 JP disclosed