Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | RARB | P10826 | 8/20 | 0.46 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7559460 | 0.88 | RARB (0.48) | MAPTRARBRARARARGMEN1 | |
| SCHEMBL7469356 | 0.87 | RARB (0.50) | MAPTRARBRARARARGMEN1 | |
| SCHEMBL7468384 | 0.84 | RARB (0.51) | MAPTRARBRARARARGMEN1 | |
| SCHEMBL7461350 | 0.84 | RARB (0.58) | MAPTRARBRARARARGMEN1 | |
| SCHEMBL7560399 | 0.81 | MAPT (0.48) | MAPTTHRBTHRARARBRARA | |
| SCHEMBL7561410 | 0.81 | MAPT (0.48) | MAPTTHRBTHRARARBRARA | |
| SCHEMBL7467756 | 0.79 | RARB (0.49) | MAPTRARBMEN1ALDH1A1KMT2A | |
| SCHEMBL11547651 | 0.78 | RARB (0.66) | MAPTTHRBTHRARARBRARA | |
| SCHEMBL11545763 | 0.78 | RARB (0.66) | MAPTTHRBTHRARARBRARA | |
| SCHEMBL11554229 | 0.78 | RARB (0.66) | MAPTTHRBTHRARARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |