Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.48 |
| ▸ | RARA | P10276 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469356 | 0.89 | RARB (0.50) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL7556985 | 0.88 | MAPT (0.48) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL7468384 | 0.86 | RARB (0.51) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL7461350 | 0.86 | RARB (0.58) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL2811008 | 0.79 | KDM4E (0.53) | MEN1ALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7521960 | 0.78 | S1PR1 (0.50) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL11467848 | 0.78 | MAPT (0.58) | ALDH1A1MAPTTP53TAS1R3TAS1R1 | |
| SCHEMBL16901835 | 0.77 | MAOA (0.46) | ALDH1A1MAPTLMNAPPARGPPARA | |
| SCHEMBL7463907 | 0.77 | LPL (0.49) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL20874436 | 0.76 | RARB (0.69) | RARBRARAMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |