Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466101 | 0.87 | RARB (0.59) | RARBMEN1KMT2ALMNATP53 | |
| SCHEMBL18611964 | 0.87 | MAOB (0.52) | ALDH1A1LMNAMAOBMAOAGAA | |
| SCHEMBL7469356 | 0.86 | RARB (0.50) | RARBHSD17B10KDM4EMEN1USP2 | |
| SCHEMBL18591911 | 0.82 | MAOB (0.52) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9119332 | 0.82 | MAOB (0.47) | HSD17B10KDM4EALDH1A1LMNAMAOB | |
| SCHEMBL11500982 | 0.81 | FLT3 (0.56) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL11446228 | 0.81 | MAPT (0.54) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL11453883 | 0.81 | ALDH1A1 (0.54) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL3497925 | 0.80 | MAOB (0.60) | HSD17B10KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL13740830 | 0.80 | CA12 (0.57) | HSD17B10KDM4EUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |