SCHEMBL7557421

SCHEMBL7557421

C=CCOc1cnc(-c2ccc(-c3ccc(CCCCCC(C)F)cc3)cc2)nc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
RAB9A P51151 4/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
USP2 O75604 2/20 0.41
KDM4E B2RXH2 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HSD17B10 Q99714 2/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
RARB P10826 5/20 0.34
POLB P06746 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
NAAA Q02083 1/20 0.30
NPC1 O15118 2/20 0.30
SPHK2 Q9NRA0 1/20 0.30
SPHK1 Q9NYA1 1/20 0.30
RARA P10276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7553869 0.99 RAB9A (0.42) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7552774 0.93 RAB9A (0.40) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7555125 0.93 RAB9A (0.40) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7560574 0.91 RARB (0.39) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7556309 0.90 RARB (0.40) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL8603584 0.89 SRC (0.34) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7556418 0.88 CYP2D6 (0.39) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL8598085 0.88 CYP2D6 (0.39) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7560826 0.87 RAB9A (0.43) MAPTRAB9AALDH1A1MEN1KMT2A
SCHEMBL7560108 0.85 RAB9A (0.44) MAPTRAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-B1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2002-01-09 EP disclosed
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed
EP-0667384-A1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-08-16 EP disclosed