SCHEMBL7560574

SCHEMBL7560574

C=CCOc1ccc(-c2ccc(-c3ncc(CCCCCC(C)F)cn3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.39
RAB9A P51151 6/20 0.36
MAPT P10636 6/20 0.36
ALDH1A1 P00352 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
KDM4E B2RXH2 3/20 0.36
HSD17B10 Q99714 2/20 0.36
USP2 O75604 2/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
NPC1 O15118 4/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 2/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7556309 0.99 RARB (0.40) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7555125 0.93 RAB9A (0.40) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7552774 0.93 RAB9A (0.40) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7557421 0.91 MAPT (0.41) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7553869 0.90 RAB9A (0.42) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7561445 0.89 SRC (0.40) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7556418 0.88 CYP2D6 (0.39) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL8598085 0.88 CYP2D6 (0.39) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL9286660 0.88 RARB (0.36) RARBRAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL7943922 0.87 RAB9A (0.51) RAB9AMAPTALDH1A1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708165-B1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL CO (JP) 2002-01-09 EP disclosed
US-6246452-B1 FERROELECTRIC CHIRAL SMECTIC LIQUID CRYSTAL MIXTURE HAVING IMPROVED RESPONSE SPEED WHICH CAN BE USED AS AN OPTICAL SHUTTER OR DISPLAY DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-12 US disclosed
EP-0667384-B1 Fluorine-containing optically active compound, process for preparing the same and liquid crystal mixture and liquid crystal element comprising the same SUMITOMO CHEMICAL CO (JP) 1998-12-16 EP disclosed
US-5779934-A FLUORINATING AN ALCOHOL DERIVATIVE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-14 US disclosed
EP-0708165-A1 Liquid crystal, liquid crystal mixture and liquid crystal device comprising the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-24 EP disclosed