Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 1.00 |
| ▸ | MMP13 | P45452 | 3/20 | 0.76 |
| ▸ | MMP3 | P08254 | 2/20 | 0.76 |
| ▸ | NAT1 | P18440 | 2/20 | 0.69 |
| ▸ | GSK3B | P49841 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557499 | 1.00 | ADAMTS5 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL7972124 | 0.89 | ADAMTS5 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL7972127 | 0.89 | ADAMTS5 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL1248883 | 0.87 | MMP13 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL8308267 | 0.87 | MMP13 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL1248886 | 0.87 | MMP13 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL18103062 | 0.85 | MMP13 (0.82) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL18103023 | 0.85 | ADAMTS5 (1.00) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL18103051 | 0.83 | NAT1 (0.83) | ADAMTS5MMP13MMP3NAT1GSK3B | |
| SCHEMBL6781138 | 0.82 | NAT1 (1.00) | ADAMTS5NAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | claimed |
| WO-2002062337-A1 | THIAZOLIDINEDIONES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-15 | — | — | WO | disclosed |