Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561126 | 0.83 | HTR2A (0.45) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL4900272 | 0.77 | HTR2A (0.55) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL4895814 | 0.77 | HTR2A (0.55) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL4887234 | 0.77 | HTR2A (0.55) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL4898274 | 0.77 | HTR2A (0.55) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL30369240 | 0.77 | HTR2A (0.55) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL7558559 | 0.76 | THRA (0.54) | HTR2AALDH1A1TP53S1PR1S1PR3 | |
| Fluoride SCHEMBL27510143 | 0.76 | GPR3 (0.50) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL31228811 | 0.75 | HTR2A (0.52) | SLC6A2SLC6A4HTR2AHTR2CDRD2 | |
| SCHEMBL2930325 | 0.75 | HTR2A (0.52) | SLC6A2SLC6A4HTR2AHTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946473-B1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECHNOLOGY GMBH (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-6168838-B1 | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) | 2001-01-02 | — | — | US | disclosed |
| EP-0946473-A1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | Aventis Research & Technologies GmbH & Co. KG. (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027035-A1 | FLUORINATED PHENANTRENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 1998-06-25 | — | — | WO | disclosed |