Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546493 | 0.88 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9122262 | 0.88 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL6966979 | 0.83 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8540324 | 0.81 | RAB9A (0.40) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7560950 | 0.78 | RARB (0.48) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7560706 | 0.78 | RARB (0.48) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7557739 | 0.77 | RARB (0.50) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7565310 | 0.77 | RARB (0.50) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7560063 | 0.77 | RARB (0.50) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7559962 | 0.77 | RARB (0.50) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638112-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-0792255-B1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING & MFG (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1996015092-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |
| US-5482650-A | Liquid crystal compounds having perfluoroether terminal portions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-09 | — | — | US | disclosed |
| US-5437812-A | Achiral and having low-temperature smectic mesophases or or latent smectic mesophases; used in mixtures with fluorinated liquid crystals; low birefringence and viscosity; high speed switches; stability | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0638112-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-15 | — | — | EP | disclosed |
| WO-1993022396-A1 | LIQUID CRYSTAL COMPOUNDS HAVING PERFLUOROETHER TERMINAL PORTIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-11-11 | — | — | WO | disclosed |