Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966979 | 0.97 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8544776 | 0.89 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8542624 | 0.83 | RAB9A (0.37) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7557759 | 0.83 | LTA4H (0.40) | SMN1; SMN2RARBNR5A1NPSR1TSHR | |
| SCHEMBL8540414 | 0.82 | NPC1 (0.42) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7561656 | 0.82 | LTA4H (0.43) | RAB9ANPC1SMN1; SMN2MAPTNR5A1 | |
| SCHEMBL7557758 | 0.81 | NPC1 (0.48) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8546600 | 0.78 | NPSR1 (0.37) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7506953 | 0.77 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL9513828 | 0.77 | NPC1 (0.65) | RAB9ANPC1SMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |