Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.52 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.52 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.52 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272137 | 0.92 | POLM (0.48) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL7560337 | 0.92 | POLM (0.48) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL22264880 | 0.91 | POLM (0.47) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL7559262 | 0.83 | LMNA (0.43) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL30666136 | 0.79 | POLM (0.67) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL16800411 | 0.75 | KDM4E (0.71) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL17369041 | 0.75 | KDM4E (0.71) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL20739827 | 0.74 | POLM (0.62) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL22261900 | 0.74 | POLM (0.62) | POLMPOLKPOLLPOLHHTR2A | |
| SCHEMBL26090058 | 0.74 | POLM (0.62) | POLMPOLKPOLLPOLHHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787005-B1 | DERMATOLOGICAL COMPOSITIONS CONTAINING BENZOYL PEROXIDE AND A COMPOUND REDUCING SKIN IRRITATION | HERMAL KURT HERRMAN GMBH (DE) | 2002-03-27 | — | — | EP | disclosed |
| US-5932228-A | ADMINISTERING BENZOYL PEROXIDE AND COMPOUND THAT REDUCES SKIN IRRITATION | THE PROCTER & GAMBLE COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| US-5545407-A | ANTIACNE AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5445823-A | Benzoyl peroxide and a compound for reducing skin irritation associated with it | THE PROCTER & GAMBLE COMPANY (US) | 1995-08-29 | — | — | US | disclosed |