SCHEMBL7558075

SCHEMBL7558075

O=[N+]([O-])C=C1SCC[S+]1[O-]

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7558072 1.00 MEN1 (0.33) MEN1ALDH1A1GAAMAPTKMT2A
SCHEMBL7556646 0.90
SCHEMBL7556654 0.90
SCHEMBL7514475 0.67
SCHEMBL7518953 0.64 ALDH1A1 (0.33) MEN1ALDH1A1GAAMAPTKMT2A
2-(Nitromethylene)Thiazolidine SCHEMBL10363912 0.58
2-(Nitromethylene)Thiazolidine SCHEMBL1871570 0.58
2-(Nitromethylene)Thiazolidine SCHEMBL1871573 0.58
SCHEMBL15868363 0.56
SCHEMBL21409043 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765870-B1 Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 2002-02-13 EP claimed
EP-0765870-A2 Broad-spectrum antimicrobially active compounds ROHM AND HAAS COMPANY (US) 1997-04-02 EP claimed
EP-0765870-B1 Broad-spectrum antimicrobially active compounds ROHM & HAAS (US) 2002-02-13 EP disclosed
US-5883134-A APPLYING 1-(ALKYLSULFINYL- OR ALKYLSULFONYL)-2-NITROETHENE DERIVATIVE AS BACTERICIDE, FUNGICIDE, AND/OR ALGICIDE ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
EP-0765870-A2 Broad-spectrum antimicrobially active compounds ROHM AND HAAS COMPANY (US) 1997-04-02 EP disclosed