Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.82 |
| ▸ | ADRB1 | P08588 | 17/20 | 0.82 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.82 |
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558376 | 1.00 | ADRB3 (0.82) | ADRB3ADRB1ADRB2BCHE | |
| SCHEMBL9683296 | 0.92 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9330198 | 0.92 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7686851 | 0.90 | ADRB3 (0.78) | ADRB3ADRB1ADRB2BCHE | |
| SCHEMBL7115574 | 0.90 | ADRB3 (0.78) | ADRB3ADRB1ADRB2BCHE | |
| SCHEMBL15275450 | 0.89 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL27478454 | 0.87 | ADRB1 (0.78) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8757924 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8757939 | 0.86 | ADRB3 (0.61) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL11220291 | 0.86 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072760-A2 | PCRA HELICASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-19 | — | — | WO | claimed |
| WO-2002072760-A2 | PCRA HELICASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-09-19 | — | — | WO | disclosed |
| EP-0772585-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004234-A1 | ARYLOXY ANDARYCTHIO PROPANOLAMINE DERIVATIVES USEFUL AS B3-ADRENORECEPTOR AGONISTS AND ANTAGONS OF THE B1 AND B2 ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |
| WO-1996004233-A1 | ARYLOXY AND ARYLTHIOPROPANOLAMINE DERIVATIVES USEFUL AS BETA 3-ADRENORECEPTOR AGONISTS AND ANTAGONISTS OF THE BETA 1 AND BETA 2-ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |