Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.86 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.86 |
| ▸ | ADRB2 | P07550 | 9/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330198 | 1.00 | ADRB3 (0.86) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7558376 | 0.92 | ADRB3 (0.82) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7558367 | 0.92 | ADRB3 (0.82) | ADRB3ADRB1ADRB2 | |
| SCHEMBL27478454 | 0.91 | ADRB1 (0.78) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9683368 | 0.89 | ADRB3 (0.74) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9683373 | 0.89 | ADRB3 (0.74) | ADRB3ADRB1ADRB2 | |
| SCHEMBL15275450 | 0.88 | ADRB3 (0.76) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7119163 | 0.88 | ADRB3 (0.79) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9817936 | 0.88 | ADRB1 (0.73) | ADRB3ADRB1ADRB2 | |
| SCHEMBL18651970 | 0.88 | ADRB3 (0.79) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| EP-0300290-B1 | PHENOXYPROPANOL AMINES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4892886-A | TREATMENT OF OBESITY, DIABETES | HOFFMAN-LA ROCHE INC. (US) | 1990-01-09 | — | — | US | disclosed |
| EP-0300290-A1 | Phenoxypropanol amines | F. HOFFMANN-LA ROCHE AG (CH) | 1989-01-25 | — | — | EP | disclosed |
| EP-0140243-A2 | Phenoxypropanol amines | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-05-08 | — | — | EP | disclosed |