SCHEMBL7558573

SCHEMBL7558573

Cc1ccc(P(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.53
TDP1 Q9NUW8 2/20 0.53
ALDH1A1 P00352 6/20 0.40
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CYP2A6 P11509 3/20 0.38
CYP1A2 P05177 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
TSHR P16473 3/20 0.37
LMNA P02545 3/20 0.37
ALOX12 P18054 1/20 0.37
PKM P14618 2/20 0.36
HTT P42858 2/20 0.36
ATM Q13315 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 1/20 0.36
NLRP1 Q9C000 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14463006 0.91 ACHE (0.44) ACHETDP1ALDH1A1CA2CA1
SCHEMBL15658046 0.86 ESR1 (0.35)
SCHEMBL1400954 0.80 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1
SCHEMBL8016825 0.78 ACHE (0.50) ACHETDP1ALDH1A1CA2CA1
SCHEMBL34181 0.76 ACHE (0.57) ACHETDP1ALDH1A1CA2CA1
SCHEMBL13975600 0.76 ESR1 (0.32) TDP1ALDH1A1
SCHEMBL15661400 0.76 ACHE (0.57) ACHETDP1ALDH1A1CA2CA1
SCHEMBL8005022 0.75 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL8015568 0.75 ACHE (0.47) ACHETDP1ALDH1A1CA2CA1
SCHEMBL5590712 0.73 ACHE (0.53) ACHETDP1ALDH1A1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2735581-B1 COMPOSITION AND POLYMER ASAHI CHEMICAL IND (JP) 2021-07-14 EP disclosed
EP-2990112-B1 METHOD FOR MANUFACTURING CATALYST FOR SYNTHESIZING CYCLIC CARBONATE MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
EP-2990113-B1 METHOD FOR PRODUCING CATALYST FOR CYCLIC CARBONATE SYNTHESIS MARUZEN PETROCHEM CO LTD (JP) 2020-03-25 EP disclosed
US-10043978-B2 Organic semiconductor formulations FLEXTERRA, INC. (US) 2018-08-07 US disclosed
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-24 US disclosed
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts MARUZEN PETROCHEMICAL CO., LTD. (JP) 2018-07-03 US disclosed
US-9834536-B2 Method for producing catalyst for cyclic carbonate synthesis NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-12-05 US disclosed
US-9738757-B2 Composition and polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2017-08-22 US disclosed
US-20170012208-A1 ORGANIC SEMICONDUCTOR FORMULATIONS USINVEST LLC 2017-01-12 US disclosed
US-20160222168-A1 Composition and Polymer ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-08-04 US disclosed
EP-0046628-A2 Process for the preparation of nickel ylides containing directly sulfonated ylide ligands GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-03-03 EP disclosed
EP-0046331-A2 Nickel ylides GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046330-A2 Process for the preparation of nickel ylides containing sulfonated group V ligands GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046329-A1 Process for the oligomerization of ethylene GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046328-A1 Process for the oligomerization of ethylene in methanol GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
EP-0046332-A2 Process for the preparation of nickel ylides containing ylide ligands with a sulfonated group V component GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-02-24 EP disclosed
US-4310716-A NICKEL YLIDE CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-01-12 US disclosed
US-4301318-A OBTAINED BY REACTING ETHYLENE USING A NICKEL YLIDE CATALYST; SOLVENT EXTRACTION OF CATALYST USING AMMONIUM HYDROXIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-11-17 US disclosed
US-4293727-A CATALYSIS WITH NICKEL YLIDE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed
US-4293502-A CATALYST FOR OLIGOMERIZATION OF ETHYLENE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1981-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10029241-B2 Method for producing catalyst for cyclic carbonate synthesis CYCS, CA7, CA9 ACHE 1194/4885TDP1 4293/4885ALDH1A1 3770/4885
US-10011621-B2 Method for producing silica gel-immobolized phosphonium salt catalysts SIK2, SIK3, SIK1 ACHE 1721/4885TDP1 3328/4885ALDH1A1 4167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.