SCHEMBL7558596

SCHEMBL7558596

OCc1nc(CO)c(CO)[nH]1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9558520 0.79
SCHEMBL9082364 0.75 GPR84 (0.46) ALDH1A1
SCHEMBL9082048 0.75 GPR84 (0.46) ALDH1A1
SCHEMBL3667065 0.73 KDM4E (0.39) KDM4EALDH1A1
SCHEMBL9281048 0.69 HTT (0.43) KDM4EMEN1KMT2AALDH1A1NPSR1
SCHEMBL4351362 0.69 KDM4E (0.31) KDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL25300630 0.63 GAA (0.42) MEN1KMT2AALDH1A1
SCHEMBL22275424 0.62
SCHEMBL3403574 0.60
SCHEMBL3829152 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0649021-B1 Reagent for endotoxin-specific assay SEIKAGAKU KOGYO CO LTD (JP) 2002-07-17 EP disclosed
EP-0613004-B1 Reagent for endotoxin assay and method for endotoxin assay using the same SEIKAGAKU KOGYO CO LTD (JP) 1998-12-23 EP disclosed
US-5840510-A KIT AND SOLUTIONS OF APROTININ AND HORSESHOE CRAB AMEBOCYTE LYSATE CONTAINING APROTININ TO INHIBIT ACTIVATION OF FACTOR G AND OTHER SERINE PROTEASES SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1998-11-24 US disclosed
US-5702882-A MIXTURE OF LIMULUS AMEBOCYTE LYSATE AND ALKYLGLUCOSIDE SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1997-12-30 US disclosed
US-5695948-A Reagent for endotoxin assay and method for endotoxin assay using the same SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) 1997-12-09 US disclosed
EP-0649021-A1 Reagent for endotoxin-specific assay SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1995-04-19 EP disclosed
EP-0613004-A1 Reagent for endotoxin assay and method for endotoxin assay using the same SEIKAGAKU KOGYO KABUSHIKI KAISHA (SEIKAGAKU CORPORATION) (JP) 1994-08-31 EP disclosed
US-4322217-A REAGENT FOR DETECTING ENDOTOXINS MALLINCKRODT, INC. (US) 1982-03-30 US disclosed