Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673721 | 0.79 | KDM4E (0.65) | KDM4EL3MBTL1NPC1HTTRAB9A | |
| SCHEMBL7748871 | 0.79 | IDO1 (0.52) | IDO1TSHRCYP3A4 | |
| SCHEMBL5611539 | 0.78 | IDO1 (0.42) | IDO1KDM4ERAB9AMAPTALDH1A1 | |
| SCHEMBL5843777 | 0.77 | IDO1 (0.52) | IDO1KDM4EMAPTALDH1A1POLB | |
| SCHEMBL4372667 | 0.76 | NPC1 (0.44) | NPC1RAB9ATDP1 | |
| SCHEMBL11698533 | 0.76 | CYP3A4 (0.41) | IDO1KDM4EL3MBTL1MAPTALDH1A1 | |
| SCHEMBL16743391 | 0.75 | IDO1 (0.42) | IDO1KDM4EL3MBTL1NPC1HTT | |
| SCHEMBL5881107 | 0.75 | CYP3A4 (0.39) | KDM4EL3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL24609573 | 0.74 | THRB (0.43) | IDO1ALDH1A1TP53TSHRHDAC3 | |
| SCHEMBL11565269 | 0.73 | GABRA1 (0.40) | KDM4EMAPTALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907684-B1 | CROSS-LINKED SILICONE BASED MATERIAL COMPRISING A BOUND PHOTOINITIATOR, ITS METHOD OF PREPARATION, HYDROPHILIC POLYMERIC PRODUCT OBTAINED FROM THIS MATERIAL AND ITS METHOD OF PREPARATION, AND NOVEL PHOTOINITIATORS | ESSILOR INT (FR) | 2002-03-27 | — | — | EP | disclosed |
| US-20010007880-A1 | Material based on crosslinked silicone polymer comprising an immobilized photoinitiator, process for the preparation thereof, hydrophilic polymeric product obtained from this material and process for the preparation thereof, and novel photoinitiators | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE | 2001-07-12 | — | — | US | disclosed |
| US-6197842-B1 | CONTACT LENSES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2001-03-06 | — | — | US | disclosed |
| EP-0907684-A1 | CROSS-LINKED SILICONE BASED MATERIAL COMPRISING A BOUND PHOTOINITIATOR, ITS METHOD OF PREPARATION, HYDROPHILIC POLYMERIC PRODUCT OBTAINED FROM THIS MATERIAL AND ITS METHOD OF PREPARATION, AND NOVEL PHOTOINITIATORS | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1999-04-14 | — | — | EP | disclosed |
| WO-1997049768-A1 | CROSS-LINKED SILICONE BASED MATERIAL COMPRISING A BOUND PHOTOINITIATOR, ITS METHOD OF PREPARATION, HYDROPHILIC POLYMERIC PRODUCT OBTAINED FROM THIS MATERIAL AND ITS METHOD OF PREPARATION, AND NOVEL PHOTOINITIATORS | ESSILOR INTERNATIONAL - COMPAGNIE GENERALE D'OPTIQUE (FR) | 1997-12-31 | — | — | WO | disclosed |