Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558767 | 1.00 | GPR119 (0.52) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL3342770 | 0.93 | GPR119 (0.59) | GPR119CHEK2ALDH1A1TPSAB1TPSD1 | |
| SCHEMBL5089073 | 0.91 | GPR119 (0.54) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL23355604 | 0.90 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL28523541 | 0.90 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL699609 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL699608 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL15376614 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL15297678 | 0.86 | GPR119 (0.56) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL6925094 | 0.85 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1174421-A1 | 3-AMIDINOBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2002-01-23 | — | — | EP | disclosed |