Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.54 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342725 | 0.93 | GPR119 (0.61) | GPR119USP30CHEK2ALDH1A1KDM1A | |
| SCHEMBL7558767 | 0.91 | GPR119 (0.52) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL7558762 | 0.91 | GPR119 (0.52) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL15297678 | 0.88 | GPR119 (0.56) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL699609 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL15376614 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL699608 | 0.88 | GPR119 (0.58) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL23355604 | 0.87 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL6925094 | 0.87 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 | |
| SCHEMBL28523541 | 0.87 | GPR119 (0.53) | GPR119USP30CHEK2PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425641-B2 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2008-09-16 | — | — | US | disclosed |
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-03-24 | — | — | US | disclosed |
| EP-1206446-B1 | CARBOXYLIC ACID AMIDES, THEIR PRODUCTION AND THEIR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F12, F11, F2 | GPR119 1071/4885USP30 4402/4885CHEK2 3103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.