SCHEMBL755907

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751937	0.76	KMT2A (0.41)	NPC1IDO1LOXL2TAAR1SMN1; SMN2
	SCHEMBL4492592	0.76	POLB (0.45)	NPC1TAAR1SMN1; SMN2TP53HPGD
	SCHEMBL509869	0.73	ALDH1A1 (0.53)	NPC1IDO1LOXL2TAAR1L3MBTL1
	SCHEMBL4677316	0.73	HTT (0.44)	TP53MAPTMEN1KMT2APOLB
	SCHEMBL16093392	0.73	TAAR1 (0.41)	NPC1TAAR1SMN1; SMN2HPGDRAB9A
	SCHEMBL3222142	0.73	TDP1 (0.58)	NPC1SMN1; SMN2RAB9AL3MBTL1MAPT
	SCHEMBL27606149	0.73	TAAR1 (0.37)	NPC1IDO1LOXL2TAAR1SMN1; SMN2
	SCHEMBL3218824	0.72	HTT (0.43)	TP53MAPTPOLBUSP2LMNA
	Bromide SCHEMBL4677319	0.72	TDP1 (0.56)	NPC1SMN1; SMN2RAB9AL3MBTL1MAPT
	SCHEMBL3221601	0.72	HTT (0.47)	TP53HPGDMAPTKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.