Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14663683 | 0.80 | CFTR (0.39) | CFTRGOPCALDH1A1CACNA1DLMNA | |
| SCHEMBL30846158 | 0.70 | KDM1A (0.37) | ALDH1A1KDM1ALMNA | |
| SCHEMBL6570406 | 0.68 | CYP1A2 (0.41) | CFTRGOPCALDH1A1HSD17B10KDM1A | |
| SCHEMBL17382164 | 0.67 | ALDH1A1 (0.44) | CFTRGOPCALDH1A1HSD17B10KDM1A | |
| SCHEMBL29560186 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA | |
| Biphenyl SCHEMBL1358618 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA | |
| Biphenyl SCHEMBL4002609 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA | |
| SCHEMBL30108088 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA | |
| Biphenyl SCHEMBL2548048 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA | |
| Biphenyl SCHEMBL164 | 0.61 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MAOACYP2B6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530389-B | Preparation method of 2-aryl cyclopropylamine compound | 东北师范大学 | 2020-06-09 | — | — | CN | claimed |
| CN-107488090-B | Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound | 东北师范大学 | 2020-06-02 | — | — | CN | claimed |
| CN-112958154-B | Application of silicon amino rare earth compound in catalyzing reaction of isatin compound and cyclopropenone compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| WO-2020241715-A1 | POLAR GROUP-CONTAINING OLEFIN COPOLYMER | 国立大学法人東京大学 | 2020-12-03 | — | — | WO | disclosed |
| CN-108530389-B | Preparation method of 2-aryl cyclopropylamine compound | 东北师范大学 | 2020-06-09 | — | — | CN | disclosed |
| CN-107488090-B | Efficient catalytic asymmetric preparation method of N-cyclopropyl nitrone compound | 东北师范大学 | 2020-06-02 | — | — | CN | disclosed |
| CN-107522635-B | N-cyclopropyl nitrone derivatives and preparation method thereof | 东北师范大学 | 2020-02-14 | — | — | CN | disclosed |
| WO-2002065216-A2 | CATIONICALLY CURABLE COMPOSITIONS CONTAINING TRIARYLCYCLOPROPENYLIUM SALTS | UCB, S.A. (BE) | 2002-08-22 | — | — | WO | disclosed |
| US-6420460-B1 | CURABLE COMPOUND RELEASING PROTONS | UCB S.A. (BE) | 2002-07-16 | — | — | US | disclosed |