SCHEMBL6570406

SCHEMBL6570406

C1=C(c2ccccc2)C(c2ccccc2)C(c2ccccc2)=C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
CYP3A4 P08684 3/20 0.41
LMNA P02545 3/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41
CFTR P13569 1/20 0.41
GOPC Q9HD26 1/20 0.41
ALDH1A1 P00352 2/20 0.40
HSD17B10 Q99714 3/20 0.39
MAOB P27338 9/20 0.37
KDM1A O60341 8/20 0.37
MAOA P21397 7/20 0.37
CYP2C19 P33261 4/20 0.37
CYP2B6 P20813 3/20 0.37
TAAR1 Q96RJ0 3/20 0.37
CYP2D6 P10635 2/20 0.37
CYP2C9 P11712 2/20 0.37
HTR1A P08908 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17480245 0.76 ALDH1A1 (0.42) CYP1A2CYP3A4LMNAMAPK1CFTR
SCHEMBL2415843 0.74 LMNA (0.34) CYP1A2CYP3A4LMNATP53MAPT
SCHEMBL7556279 0.72 LMNA (0.46) CYP1A2CYP3A4LMNATP53MAPT
Bromide SCHEMBL28349964 0.70 LMNA (0.44) CYP1A2CYP3A4LMNATP53MAPT
SCHEMBL23074143 0.70 ALDH1A1 (0.42) CYP1A2CYP3A4LMNAMAPTMAPK1
SCHEMBL21546182 0.69 HSD17B10 (0.32) CYP3A4CFTRGOPCALDH1A1HSD17B10
SCHEMBL7559097 0.68 CFTR (0.41) CYP1A2LMNACFTRGOPCALDH1A1
SCHEMBL20860346 0.68 MAOB (0.33) CYP1A2CYP3A4LMNACFTRGOPC
SCHEMBL17382164 0.67 ALDH1A1 (0.44) CYP1A2CYP3A4LMNAMAPK1CFTR
SCHEMBL18691989 0.67 LMNA (0.41) CYP1A2CYP3A4LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1404446-A2 CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS Sasol Technology (Proprietary) Limited (ZA) 2004-04-07 EP disclosed
WO-2003004158-A2 CATALYST COMPRISING CHROMIUM AND A LIGAND COMPRISING A SUBSTITUTED CYCLOPENTADIENE AND ITS USE FOR TRIMERISING OLEFINS SASOL TECHNOLOGY (PROPRIETARY) LIMITED (ZA) 2003-01-16 WO disclosed