Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15914232 | 0.93 | GABRA1 (0.50) | GABRA1GABRB2ELANELMNATSHR | |
| SCHEMBL10507496 | 0.89 | GABRA1 (0.58) | GABRA1GABRB2ELANELMNATSHR | |
| SCHEMBL11463024 | 0.85 | ESR1 (0.46) | GABRA1GABRB2ELANETSHRCA1 | |
| SCHEMBL10410201 | 0.85 | ESR1 (0.46) | GABRA1GABRB2ELANETSHRCA1 | |
| SCHEMBL9203522 | 0.84 | ELANE (0.33) | GABRA1GABRB2ELANE | |
| SCHEMBL8113334 | 0.84 | CYP3A4 (0.38) | GABRA1GABRB2ELANELMNATSHR | |
| SCHEMBL17417908 | 0.84 | ELANE (0.33) | GABRA1GABRB2ELANE | |
| Iodide SCHEMBL11335497 | 0.80 | LMNA (0.41) | ELANELMNAHIF1ATRPA1ALDH1A1 | |
| SCHEMBL6553219 | 0.80 | MYC (0.39) | GABRA1GABRB2ELANETSHRCYP1A2 | |
| SCHEMBL17515123 | 0.80 | GABRA1 (0.68) | GABRA1GABRB2LMNATSHRGABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506314-B1 | Process for preparing vinylically-unsaturated compounds | DOW CHEMICAL CO (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5264646-A | Vinylation, benzocyclobutenes, polysiloxanes | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5243068-A | Alkenylation with organic halides | THE DOW CHEMICAL COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0506314-A2 | Process for preparing vinylically-unsaturated compounds | THE DOW CHEMICAL COMPANY (US) | 1992-09-30 | — | — | EP | disclosed |
| US-5136069-A | Reacting with halogenated organic compound in presence of palladium complex catalyst and inorganic hydrogen halide acceptor | THE DOW CHEMICAL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |