Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ERN1 | O75460 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926340 | 0.86 | ERN1 (0.46) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL5075020 | 0.84 | CYP2A13 (0.58) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL23926337 | 0.83 | SIGMAR1 (0.48) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL29417692 | 0.82 | CYP2A13 (0.56) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL19603399 | 0.82 | CYP2A13 (0.56) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL17724305 | 0.82 | CYP2A13 (0.56) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL16243516 | 0.79 | CYP2A13 (0.49) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL16119943 | 0.78 | ERN1 (0.53) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL3086221 | 0.78 | ERN1 (0.62) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 | |
| SCHEMBL19603394 | 0.78 | CYP2A13 (0.45) | CYP2C9ALOX15HSD17B10ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168408-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2023-04-26 | — | — | EP | disclosed |
| CN-115667256-A | Compounds for treating diseases and methods of treating diseases | 艾特里提治疗有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021253091-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2021-12-23 | — | — | WO | disclosed |
| WO-2021253091-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2021-12-23 | — | — | WO | disclosed |
| US-11155547-B1 | Compounds for and methods of treating diseases | Alterity Therapeutics Limited (AU) | 2021-10-26 | — | — | US | disclosed |
| US-11155547-B1 | Compounds for and methods of treating diseases | Alterity Therapeutics Limited (AU) | 2021-10-26 | — | — | US | disclosed |
| EP-1169269-A1 | EXTRACTION OF METAL SALTS FROM AQUEOUS SOLUTIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000058225-A1 | EXTRACTION OF METAL SALTS FROM AQUEOUS SOLUTIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11155547-B1 | Compounds for and methods of treating diseases | HTT, SNCA, PARK7 | CYP2C9 4492/4885ALOX15 214/4885HSD17B10 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.