Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.44 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | S100B | P04271 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993806 | 0.93 | L3MBTL1 (0.43) | PRMT1F2ST14PLAUTMPRSS2 | |
| SCHEMBL1148129 | 0.89 | L3MBTL1 (0.42) | PRSS1 | |
| SCHEMBL7554944 | 0.86 | PPARA (0.57) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL27734552 | 0.84 | PPARA (0.58) | HDAC1HDAC2GAAHDAC3HDAC4 | |
| SCHEMBL7773663 | 0.81 | HDAC1 (0.67) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7768493 | 0.81 | HDAC1 (0.67) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL5544236 | 0.81 | HDAC1 (0.47) | HDAC1HDAC2GAAHDAC3HDAC4 | |
| SCHEMBL6849706 | 0.79 | KCNA3 (0.64) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL5542764 | 0.79 | TSHR (0.45) | HDAC1HDAC2GAAHDAC3HDAC4 | |
| SCHEMBL5803799 | 0.78 | PPARA (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219631-A1 | ANTIANDROGEN AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-07-03 | — | — | EP | disclosed |