Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 8/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928544 | 0.85 | RARB (0.42) | RARBRARARARGS1PR1S1PR4 | |
| SCHEMBL7564880 | 0.76 | RARB (0.53) | RARBRARARARGMPLHTR2A | |
| SCHEMBL8023518 | 0.75 | S1PR1 (0.52) | RARBRARARARGS1PR1S1PR4 | |
| SCHEMBL13310859 | 0.75 | S1PR1 (0.52) | RARBRARARARGS1PR1S1PR4 | |
| SCHEMBL9417091 | 0.75 | S1PR1 (0.47) | RARBS1PR1S1PR4S1PR5S1PR2 | |
| SCHEMBL5722713 | 0.75 | TDO2 (0.34) | — | |
| SCHEMBL8024024 | 0.74 | RARB (0.51) | RARBRARARARGS1PR1HTR2A | |
| SCHEMBL10533738 | 0.71 | RARB (0.58) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9493854 | 0.71 | RARB (0.58) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL9494751 | 0.71 | RARB (0.58) | RARBRARARARGHTR2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944565-B1 | 1,3,5-TRIFLUORONAPHTHALENE DERIVATIVES FOR LIQUID CRYSTALLINE MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2002-07-31 | — | — | EP | disclosed |