Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7556733 | 0.90 | MEN1 (0.43) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7553645 | 0.89 | MAPT (0.37) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7557951 | 0.88 | HSD17B10 (0.40) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7556110 | 0.86 | TSHR (0.41) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7550221 | 0.77 | KMT2A (0.46) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7552047 | 0.76 | HSD17B10 (0.39) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL7557970 | 0.76 | TSHR (0.41) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL9304224 | 0.76 | MAPT (0.51) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7559624 | 0.76 | MAPT (0.51) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7555575 | 0.75 | LMNA (0.32) | MAPTALDH1A1HSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0734380-B1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6369270-B1 | CHEMICAL INTERMEDIATES | RHONE POULENC AGRICULTURE LIMITED (GB) | 2002-04-09 | — | — | US | disclosed |
| US-6114538-A | 2-POSITION OF BENZOY RING OF 4-BENZOYLISOXAZOLE DERIVATIVE IS SUBSTITUTED AND PARTICULARLY USED AGAINST MONOCOTYLEDONOUS WEEDS BY POST-EMEREGENECE APPLICATION | RHONE POULENC AGRICULTURE LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| US-5998653-A | CHEMICAL INTERMEDIATE FOR HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1999-12-07 | — | — | US | disclosed |
| US-5658858-A | POSTEMERGENCE HERBICIDES | RHONE-POULENC ARGRICULTURE LIMITED (GB) | 1997-08-19 | — | — | US | disclosed |
| EP-0734380-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1996-10-02 | — | — | EP | disclosed |
| WO-1995016678-A1 | 4-BENZOYLISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-06-22 | — | — | WO | disclosed |