Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554484 | 0.85 | MMP3 (0.40) | AKR1C3MEN1KMT2A | |
| SCHEMBL7559368 | 0.83 | MMP2 (0.43) | MMP8 | |
| SCHEMBL7552746 | 0.72 | MMP2 (0.48) | MMP8TDP1 | |
| SCHEMBL7559383 | 0.71 | TDP1 (0.40) | TDP1 | |
| SCHEMBL27518207 | 0.68 | TDP1 (0.61) | TDP1MEN1KMT2A | |
| SCHEMBL7365648 | 0.68 | TDP1 (0.39) | TDP1CAPN1 | |
| SCHEMBL2153187 | 0.66 | TDP1 (0.54) | TDP1MEN1KMT2A | |
| Methyl 3-Phenylpropanoate SCHEMBL28250358 | 0.66 | TDP1 (0.54) | TDP1KMT2A | |
| SCHEMBL3183513 | 0.65 | TSHR (0.68) | TDP1AKR1C3MEN1KMT2A | |
| SCHEMBL24437485 | 0.64 | TDP1 (0.51) | TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925278-B1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2002-07-17 | — | — | EP | claimed |