Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558781 | 0.92 | MAPT (0.40) | MAPTHSD17B1HSD17B2TDP1PARP1 | |
| SCHEMBL7557389 | 0.86 | MAPT (0.43) | MAPTHSD17B1HSD17B2PIK3C3KDM4E | |
| SCHEMBL7558377 | 0.85 | MAPT (0.42) | MAPTHSD17B1HSD17B2PIK3C3TDP1 | |
| SCHEMBL7558786 | 0.83 | MAPT (0.41) | MAPTHSD17B1HSD17B2PIK3C3PARP1 | |
| SCHEMBL7563319 | 0.78 | HTR1A (0.36) | MAPTHSD17B1HSD17B2KDM4EGPBAR1 | |
| SCHEMBL7558487 | 0.78 | MAPT (0.41) | MAPTHSD17B1HSD17B2PIK3C3KDM4E | |
| SCHEMBL6204567 | 0.77 | HDAC4 (0.49) | MAPTGPBAR1 | |
| SCHEMBL7557878 | 0.77 | MAPT (0.39) | MAPTHSD17B1HSD17B2PIK3C3PARP1 | |
| SCHEMBL7561988 | 0.77 | MAPT (0.40) | MAPTTDP1KDM4EDAOGSK3B | |
| SCHEMBL7826245 | 0.76 | NPSR1 (0.39) | MAPTPARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | Active Biotech AB (SE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001030758-A1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2001-05-03 | — | — | WO | claimed |