Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.36 |
| ▸ | RXRG | P48443 | 12/20 | 0.36 |
| ▸ | RXRB | P28702 | 11/20 | 0.36 |
| ▸ | RARB | P10826 | 7/20 | 0.36 |
| ▸ | RARG | P13631 | 6/20 | 0.36 |
| ▸ | RARA | P10276 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472789 | 1.00 | RXRA (0.36) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7563931 | 0.91 | RXRA (0.39) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6478019 | 0.91 | RXRA (0.39) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6473196 | 0.86 | RXRA (0.46) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7558629 | 0.86 | RXRA (0.46) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7560513 | 0.85 | RXRA (0.40) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7560510 | 0.85 | RXRA (0.40) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL7558455 | 0.83 | RARB (0.38) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6472723 | 0.83 | RARB (0.38) | RXRARXRGRXRBRARBRARG | |
| SCHEMBL6473487 | 0.83 | RXRA (0.41) | RXRARXRGRXRBRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986537-B1 | NOVEL HETEROETHYNYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME | GALDERMA RES & DEV (FR) | 2002-08-07 | — | — | EP | claimed |